Ayrton Senna (1960–1994), Brazilian F1 driver and triple World Champion
Bruno Senna (born 1983), F1 driver and nephew of Ayrton Senna
Danzy Senna (born 1970), novelist
Lorraine Senna, American film and television director
Marcos Senna (born 1976), Brazilian-Spanish football player
Márcio Senna (born 1981), Brazilian football player, Marcos's brother
Mohammad Ibrahim Abu Senna (born 1937), Egyptian poet
Viviane Senna (born 1958), IAS president and sister of Ayrton Senna
Senna Gammour (born 1979), German singer and member of Monrose (2006–2011)
Senna Proctor (born 1998), British racing driver
Senna Ušić-Jogunica (born 1986), Croatian volleyball player
Fictional characters
Senna Galan, a character in the American action-drama TV series Matador. She is the daughter of Andrés Galan, one of the protagonists.
Senna Refa, a character in the Babylon 5 novel Legions of Fire – Out of the Darkness. She is the daughter of Antono Refa
Senna is also the name of another, unrelated Centauri woman: the governess seen in Babylon 5: In the Beginning. She was an old retainer of House Jaddo.
Senna Tōno, a character in the visual novel W Wish series.
Senna Wales, a witch in the Everworld fantasy series for young adults by K. A. Applegate
Senna, a character in the movie Bleach: Memories of Nobody
Senna, a character in the League of Legends series
Senna is the mother of Avatar Korra in the Nickelodeon animated series Avatar: The Legend of Korra
Plants
Senna (plant), a genus of legumes
Formerly, plants in Cassia (genus) which used to include Senna
Black senna the Scrophulariaceae genus Seymeria
Bladder sennas, the legume genus Colutea
Scorpion sennas, plants in the legume genera Coronilla and Hippocrepis
Places
Senna Comasco, a comune (municipality) in the Province of Como in the Italian region Lombardy
Senna Lodigiana, a comune (municipality) in the Province of Lodi in the Italian region Lombardy
Senna (Sihnah, Sihneh), a Kurdish city in western Iran, nowadays Sanandaj.
Other
Senna (poetic), an exchange of insults found in the Poetic Edda
Senna (film), a 2010 documentary film about Ayrton Senna
Senna (miniseries), a 2024 Netflix series about Ayrton Senna
McLaren Senna, a British mid-engined sports car, honouring Ayrton Senna