List of chemotherapeutic agents

This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer. This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision. Each drug is listed once (at present), though it might fall in more than one subsection. A full alphabetical listing is included after the categorical listing.

The agents in this list are often combined into chemotherapy agent for polychemotherapy (combination chemotherapy). For example, the CHOP regimen consists of cyclophosphamide, doxorubicin, vincristine and prednisone.

Besides chemotherapy, medical oncology (pharmacotherapy for cancer) includes several noncytotoxic classes of therapy, such as hormonal therapy and targeted therapy (biologic therapy). Those agents are described in the relevant articles.

Alkylating agents

• Altretamine
• Bendamustine
• Busulfan
• Carboquone
• Carmustine
• Chlorambucil
• Chlormethine
• Chlorozotocin
• Cyclophosphamide
• Dacarbazine
• Fotemustine
• Ifosfamide
• Lomustine
• Melphalan
• Melphalan flufenamide
• Mitobronitol
• Nimustine
• Nitrosoureas
• Pipobroman
• Ranimustine
• Semustine
• Streptozotocin
• Temozolomide
• Thiotepa
• Treosulfan
• Triaziquone
• Triethylenemelamine
• Trofosfamide
• Uramustine

Anthracyclines

Aclarubicin

• Daunorubicin
• Doxorubicin
• Epirubicin
• Idarubicin
• Mitoxantrone
• Pirarubicin
• Valrubicin
• Zorubicin

Cytoskeletal disruptors (taxanes)

• Abraxane
• Cabazitaxel
• Docetaxel
• Larotaxel
• Paclitaxel
• Taxotere
• Tesetaxel

Epothilones

• Ixabepilone

Histone deacetylase inhibitors

• Entinostat
• Romidepsin
• Vorinostat
• Zabadinostat

Inhibitors of topoisomerase I

• Belotecan
• Camptothecin
• Exatecan
• Gimatecan
• Irinotecan
• Topotecan

Inhibitors of topoisomerase II

• Etoposide
• Teniposide
• Tafluposide

Kinase inhibitors

• Bortezomib
• Erlotinib
• Gefitinib
• Imatinib
• Vemurafenib
• Vismodegib

Nucleotide analogs and precursor analogs

• Azacitidine
• Azathioprine
• Capecitabine
• Cytarabine
• Doxifluridine
• Fluorouracil
• Gemcitabine
• Hydroxyurea
• Mercaptopurine
• Methotrexate
• Tioguanine (formerly Thioguanine)

Peptide antibiotics

• Actinomycin
• Bleomycin

Platinum-based agents

• Carboplatin
• Cisplatin
• Dicycloplatin
• Oxaliplatin
• Nedaplatin
• Satraplatin

Retinoids

• Alitretinoin
• Bexarotene
• Tretinoin

Vinca alkaloids and derivatives

• Vinblastine
• Vincristine
• Vindesine
• Vinorelbine

Full alphabetical listing

Comprehensive table

1. Chemotherapy
2. List of antineoplastic agents
3. Alkylating antineoplastic agent
4. Anti-Cancer Agents in Medicinal Chemistry
5. Nitrogen mustard
6. Mitomycin C
7. Antifungal
8. Ouzo effect
9. Chemistry of ascorbic acid
10. List of hormonal cytostatic antineoplastic agents
11. Chemoprotective agent
12. Kidney disease
13. Mesna
14. Chemotherapy-induced nausea and vomiting
15. Chlormethine
16. Atypia
17. ATC code L01
18. Carmustine
19. Bone metastasis
20. Azelaic acid