Eponymous character in the song "Lucy in the Sky with Diamonds" by the Beatles, said to be based on a drawing of Lucy O'Donnell or the LSD abbreviation
Lucy and the Diamonds, antagonists in the film Sgt. Pepper's Lonely Hearts Club Band based around the song
Lucy Carrigan, a main character in the film Across the Universe based loosely around the song
Lucy Coe (General Hospital)
Lucy Maria Misora, an alien character in the Japanese adult visual novel ToHeart2'
Lucy Camden-Kinkirk in the TV series 7th Heaven
Lucy Robinson in the Australian television soap opera Neighbours
Lucy Knight in the TV series ER
Lucy Cunningham-Schultz in the radio drama Adventures in Odyssey
Lucy Snowe, heroine of Villette by Charlotte Brontë
Lucy Barker in Stephen Sondheim's Sweeney Todd: The Demon Barber of Fleet Street
Lucy Harris in Frank Wildhorn'sJekyll & Hyde
Lucy Dennison in Richie Tankersley Cusick's books series The Unseen
Lucy Tartan, a major character in Herman Melville's novel Pierre: or, The Ambiguities
Lucy Wilde in Despicable Me 2
Titular protagonist of the 2014 sci-fi/action film Lucy
Lucy Lane, sister of Superman's girlfriend Lois Lane
Lucy Saxon, the Master's ex-wife from the third series and 2008–2010 specials of the Doctor Who revival series
Lucy Stillman, recurring character in Assassin's Creed
Lucy Loud, in the TV series The Loud House
Lucy Carlyle, main character in the Lockwood and Co. series by Jonathan Stroud.