OD or o.d., an abbreviation used in medical prescriptions for omne in die or "once daily" both meaning "take once every day"
Doctor of Optometry (O.D.)
Oculus dexter, ocular dexter, or ocularis dexter, meaning "right eye" in general ophthalmologic or optometric usage, particularly in eyeglass prescriptions
Osteochondritis dissecans, a medical disease affecting the joints of both humans and animals
Overdose, the inadvertent drug effects of the user rendered unresponsive or fatally succumbed due to unsophistication of self-medicating being unaccustomed to quantities greater than recommended
Music
Oblivion Dust, a Japanese rock band
Old Dominion (band), an American country music band
One Direction, a British/Irish pop music band
Orphei Drängar, a Swedish male choir
The OD EP, a 2012 extended play by Danny Brown
Overly Dedicated, a 2010 mixtape by Kendrick Lamar
"O.D", a song by Sunna from the album One Minute Science (2000)
"OD", an alternative name for the song "DTM" by SZA from Lana (2024)
Organizations
Batik Air Malaysia (IATA airline code OD)
Ordnungsdienst, Jewish order service in ghettos during the war
Organization development
People and characters
Super OD, a Ghanaian actor
O.D (Gatchaman Crowds), a character in the anime series Gatchaman Crowds