Progonadotropin

A progonadotropin, or hypergonadotropin, also known as a gonad stimulant, is a type of drug which increases the secretion of one or both of the major gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This, in turn, results in increased function and maintenance of the gonads and increased gonadal steroidogenesis of sex hormones such as androgens, estrogens, and progestogens. Progonadotropins are the functional opposites of antigonadotropins. They have clinical applications in the treatment of hypogonadism and infertility. Conversely, hypergonadotropic effects can occur as a side effect of some drugs. Examples of progonadotropic drugs include gonadotropin-releasing hormone (GnRH) agonists when administered in a pulsatile (as opposed to continuous) manner, antiestrogens such as tamoxifen, clomifene, fulvestrant, and aromatase inhibitors like anastrozole, and, only in men, pure antiandrogens such as flutamide, bicalutamide, enzalutamide, and apalutamide.

References

External links

• Media related to Progonadotropins at Wikimedia Commons

1. Enclomifene
2. Gonadotropin-releasing hormone agonist
3. Gonadotropin-releasing hormone
4. Estrogen
5. Androgen
6. Oxandrolone
7. Testosterone
8. Dehydroepiandrosterone
9. Trenbolone
10. Finasteride
11. Metenolone enanthate
12. Hormone replacement therapy
13. Anabolic steroid
14. Dihydrotestosterone
15. Oxymetholone
16. Feminizing hormone therapy
17. Spironolactone
18. Trenbolone acetate
19. Testosterone propionate
20. Pharmacokinetics of estradiol