Estradiol valerate/prasterone enanthate

Estradiol valerate/prasterone enanthate (EV/DHEA-E), sold under the brand name Gynodian Depot among others, is an injectable combination medication of estradiol valerate (EV), an estrogen, and prasterone enanthate (DHEA-E), an androgen, estrogen, and neurosteroid, which is used in menopausal hormone therapy for women. It is provided in the form of 1 mL ampoules containing 4 mg estradiol valerate and 200 mg prasterone enanthate in an oil solution and is administered by intramuscular injection once every 4 to 6 weeks. EV/DHEA-E reportedly has a duration of about 21 days.

The medication is available in Europe, Latin America, and Egypt. EV/DHEA-E was developed and marketed by Schering, was first described in the literature in 1972, and was introduced for medical use in April 1975.

See also

• List of combined sex-hormonal preparations

References

1. Estradiol valerate
2. Prasterone enanthate
3. Estradiol enantate
4. Estradiol valerate/testosterone enanthate
5. Pharmacokinetics of estradiol
6. Prasterone
7. Estradiol cypionate
8. Estradiol benzoate
9. Estradiol/estradiol enanthate
10. Estradiol (medication)
11. Norethisterone enanthate
12. Estradiol valerate/dienogest
13. Estradiol benzoate/estradiol valerate/norethisterone acetate/testosterone enanthate
14. Estradiol undecylate
15. Estradiol valerate/cyproterone acetate
16. Estradiol-containing birth control pill
17. Dienogest
18. Estradiol cypionate/testosterone enanthate
19. Estradiol benzoate/estradiol valerate/hydroxyprogesterone caproate
20. Estradiol valerate/methenmadinone caproate